of Guillan- Barre syndrome in Immam Hossain Hospital& Shohada
1 -Soltanzadeh M.H.
Pofessor of pediatrics ,Shahid
Bheshti University of Medical Science ,Tehran ,Iran
2- Shirvani F.
Assistant professor of pediatrics ,Shahid
Beheshti University of medical science ,Tehran, Iran
3 -Afsari K. GP
Guillan – Barre syndrome is a major cause of
acute neuromuscular paralysis considering the controversy
surrounding its epidemiology, pathology, diagnosis , and treatment,
the medical files of children admitted to Immam Hossain Hospital and
Shohada hospital from 1993-2003 with a diagnosis of Guillan-Barre
syndrome were studied to determine the epidemiology of this
A total 42 children were included in this
study of existing data , patients age , sex, family history signs
and symptoms , disease course, diagnostic criteria and mortality
rate were studied .
The incidence was 1.5 times grater in boy
compared to girls , age ranged from 9 months to 14 years with a
mean age of years ,family history showed no remarkable pattern, in
42.8 % a history of Respiratory or Gastrointestinal infection 10-14
days before onset of diseases was noted. The most common sign was
lower extremity weakness , urinary incontinence was observed in 4.7
% , The physical exam showed hyporeflexia and areflexia to be the
most common finding in 38 % , facial nerve paralysis was observed
, in all patients LP was performed . in 69 % protein was reported to
be above normal with mild pleocytosis . in 21 patients EMG was
performed and disturbances were seen in 61.9 % although necessary
treatment measures were taken , mortality was reported in 4.7 % .
Key Word : Guillan
– Barre sydrome, acute paralysis of neuromuscular